inhalable particles comprising tiotropium and indacaterol

摘要

The present invention relates to inhalable particles comprising an intimate mixture consisting of a) an amorphous tiotropium compound, b) an amorphous indacaterol compound, and c) a sugar derivative, wherein the weight of the Sugar is comprised of 0 to 85% by weight of the inhalable particles. It also relates to a pharmaceutical composition comprising the inhalable particles of the invention, a process for their preparation, and their use in the treatment of asthma or chronic obstructive pulmonary disease (COPD).