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Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
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机译:细胞因子生物标志物作为醋酸格拉替雷临床反应的预测性生物标志物
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摘要
A method for treating a human subject afflicted with multiple sclerosis or a single clinical attack consistent with multiple sclerosis with a pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier, comprising the steps of determining whether the human subject is a glatiramer acetate responder by evaluating a biomarker selected from the group consisting of IL-17 concentration, TNF- concentration, IL-2 concentration and IFN- concentration, or a combination thereof, in the blood of the human subject and administering the pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier to the human subject only if the human subject is identified as a glatiramer acetate responder.
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