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METHODS OF SYNTHESIS OF INGENOL AND INTERMEDIATES THEREOF
METHODS OF SYNTHESIS OF INGENOL AND INTERMEDIATES THEREOF
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机译:GEN子酚的合成及其中间体的方法
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摘要
The present invention relates generally to methods of synthesis of diterpene heterocylic compounds. More particularly, the present invention relates to efficient methods of synthesis of ingenol (Formula (21), CAS 30220-46-3), from a compound of formula (1). The present invention also provides for various advantageous intermediates along the synthetic route of ingenol. Efficient synthesis of ingenol is important in the design and synthesis of related analogues, such as ingenol-3-angelate.
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