首页> 外国专利> MESOPOROUS SILICA NANOPARTICLES AND SUPPORTED LIPID BI-LAYER NANOPARTICLES FOR BIOMEDICAL APPLICATIONS

MESOPOROUS SILICA NANOPARTICLES AND SUPPORTED LIPID BI-LAYER NANOPARTICLES FOR BIOMEDICAL APPLICATIONS

机译:用于生物医学的介孔二氧化硅纳米粒子和支持的脂质双层纳米粒子

摘要

The present disclosure is directed to methods of producing monosized protocells from monosized mesoporous silica nanoparticles (mMSNPs) and their use for targeted drug delivery formulations and systems and for biomedical applications. The present disclosure is also directed in part to a multilamellar or unilamellar protocell vaccine to deliver full length viral protein and/or plasmid encoded viral protein to antigen presenting cells (APCs) in order to induce an immunogenic response to a virus.
机译:本公开内容涉及由单一尺寸的中孔二氧化硅纳米粒子(mMSNP)产生单一尺寸的原始细胞的方法及其在靶向药物递送制剂和系统以及生物医学应用中的用途。本公开还部分涉及多层或单层原细胞疫苗,其将全长病毒蛋白和/或质粒编码的病毒蛋白递送至抗原呈递细胞(APC),以诱导对病毒的免疫原性应答。

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