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PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR THE SYNTHESIS OF I.A. CARFILZOMIB
PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR THE SYNTHESIS OF I.A. CARFILZOMIB
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机译:I.A.合成中间体的制备方法卡非佐米
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摘要
The present invention provides a compound which is the trichloroacetic acid salt of a compound of Formula (II) wherein R is selected from the group consisting of H, CH3-, (CH3)2CH-, (CH3)2CHCH2-, CH3CH2CH(CH3)-, and PhCH2-, and a process for its preparation.;Also provided is a process for its preparation based on the stereoselective epoxidation of the corresponding olefin precursor and a process for the preparation of several pharmaceutically active ingredients comprising the preparation of the compound of formula (II).
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