LIVER-TYPE FATTY-ACID BINDING PROTEIN MARKER, EVALUATION METHOD OF MARKER, METHOD OF SUPPRESSING FLUCTUATION RANGE OF MEASURED VALUE RESULTING FROM LIVER-TYPE FATTY ACID BINDING PROTEIN MEASURED USING MARKER, METHOD OF FORMING CALIBRATION CURVE OF LIVER-TYPE FATTY ACID BINDING PROTEIN, AND METHOD OF QUANTIFYING PROTEIN

摘要

PROBLEM TO BE SOLVED: To provide a liver-type fatty acid binding protein marker that can reduce the range of fluctuations of measured values resulting from liver-type fatty acid binding protein measured using a substance that specifically binds thereto, a method of evaluating said marker, a method of creating a calibration curve of the liver-type fatty acid binding protein, and method of quantifying protein.;SOLUTION: The liver-type fatty acid binding protein marker comprises an amino acid sequence with 90% or more sequence identity to sequence number 1 in the sequence table in which the oxidation rate of the methionine at position 19 is 30% or more, and the oxidation rate of the methionine at position 113 is 70% or more. The liver-type fatty acid binding protein marker comprises a liver-type fatty acid binding protein comprising an amino acid sequence with 90% or more sequence identity to sequence number 1 in the sequence table and, with respect to the molar ratio of the liver-type fatty acid binding protein, the molar ratio of at least one type of fatty acid selected from the group consisting of arachidonic acid, oleic acid, 8-isoprostaglandin F_2α and 2,3-dinor-8-isoprostaglandin F_2α is 30 times or more.;SELECTED DRAWING: Figure 1;COPYRIGHT: (C)2018,JPO&INPIT