首页> 外国专利> Methods for evaluating liver-type fatty acid binding protein preparation, a method for evaluating the same, a method for suppressing the fluctuation range of measured values caused by liver-type fatty acid binding protein in measurement using the above-mentioned product, a calibration curve for liver-type fatty acid binding protein Method for making and quantifying said protein

Methods for evaluating liver-type fatty acid binding protein preparation, a method for evaluating the same, a method for suppressing the fluctuation range of measured values caused by liver-type fatty acid binding protein in measurement using the above-mentioned product, a calibration curve for liver-type fatty acid binding protein Method for making and quantifying said protein

机译:肝型脂肪酸结合蛋白制剂的评价方法,评价方法,使用上述产品抑制测定中的肝型脂肪酸结合蛋白引起的测定值的变动范围的方法,校正曲线肝型脂肪酸结合蛋白的制备和定量方法

摘要

To provide a liver-type fatty acid binding protein preparation capable of reducing a fluctuation range of a measurement value caused by a liver-type fatty acid binding protein in a measurement using a substance that specifically binds.SOLUTION: A liver having an oxidation rate of 90% or more identity with a specific sequence of a fatty acid binding protein, an oxidation rate of the 19th methionine of 30% or more, or an oxidation rate of the 113th methionine of 70% or more Type liver fatty acid binding protein preparation containing fatty acid binding protein. To the molar amount of liver-type fatty acid binding protein, arachidonic acid, oleic acid, 8-isoprostaglandin F2And 2,3-dinor-8-isoprostaglandin F2, A molar amount of at least one fatty acid selected from the group consisting of liver type fatty acid binding protein containing a hepatic fatty acid binding protein having an amino acid sequence having 90% or more identity with the specific sequence .(FIG.
机译:提供一种肝型脂肪酸结合蛋白制剂,该制剂能够在使用特异性结合物质的测定中减少由肝型脂肪酸结合蛋白引起的测定值的波动范围。与特定类型的脂肪酸结合蛋白的序列具有90%或更高的同一性,第19个蛋氨酸的氧化率达到30%或更高,或第113蛋氨酸的氧化率达到70%或更高脂肪酸结合蛋白。相对于肝脏型脂肪酸结合蛋白,花生四烯酸,油酸,8-异前列腺素F 2 和2,3-dinor-8-异前列腺素F 2 的摩尔量摩尔量的选自肝型脂肪酸结合蛋白的至少一种脂肪酸的摩尔量,所述肝型脂肪酸结合蛋白包含具有与特定序列具有90%或更高同一性的氨基酸序列的肝脂肪酸结合蛋白。

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