Lipoprotein-related phospholipase A2 (Lp-PLA2) inhibitors based on 2,3-dihydroimidazole 1,2-c pyrimidin-5 (1H) -one

摘要

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.