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COMPOSITIONS AND METHODS FOR SPECIFIC REACTIVATION OF HIV LATENT RESERVOIR
COMPOSITIONS AND METHODS FOR SPECIFIC REACTIVATION OF HIV LATENT RESERVOIR
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机译:HIV潜伏储层特定活化的组合物和方法
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摘要
The present invention relates to compositions and methods for reactivation of HIV in vivo or in vitro. latently infected cell. In one embodiment, the present invention uses the CRISPR/Cas9 system in combination with the MS2 bacteriophage coat protein-mediated synergistic activation mediator (SAM) system to provide enhanced transcriptional activation of the HIV genome.
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