a method for preventing or reducing norleukin incorporation and for producing a protein or polypeptide in a bacterial host cell, microorganism, anti-vegf antibody or anti-vegf antibody fragment, anti-factor d antibody or anti-factor antibody fragment anti-met antibody or anti-met antibody fragment

摘要

The present invention relates to methods and compositions for preventing incorporation of norleucine into proteins during recombinant protein production in bacteria. The present invention also provides microorganism host cells and nucleic acid molecules for use with the methods and compositions provided herein.