therapeutic agent, use of a therapeutic agent, in vitro methods for determining whether a subject with melanoma has a higher risk of metastasis, determining a treatment regimen for a subject suffering from melanoma, treating a subject suffering from melanoma, in vitro test to predict increased risk of metastasis and kits

摘要

The present invention relates, inter alia, to therapeutic agents for use in the treatment of melanoma, methods of diagnosing an increased risk for metastasis in a subject suffering from melanoma, methods of treating such subjects, diagnostic assays, and kits. . More specifically, in certain embodiments, the invention relates to identifying whether a subject suffering from melanoma has a higher risk of metastasis by determining the expression of ambra-1 and loricrin in a tissue sample obtained from said subject. .