method for inducing meiotic recombinations addressed in a eukaryotic cell, fusion protein, nucleic acid, expression cassette or a vector, host cell, method for generating variants of a eukaryotic organism, method for identifying or locating genetic information, kit, and, use of a kit

摘要

The present invention relates to a fusion protein comprising a cas9 domain and a spo11 domain, as well as the use of such a protein to induce addressed meiotic recombinations in a eukaryotic cell.