methods for treating a solid tumor, a malignant thyroid tumor, head and neck squamous cell cancer (ccecp), a salivary gland tumor, cancer, chronic myelomonocytic leukemia, and myelodysplastic syndrome (smd) in an individual, method for selecting one cancer patient for fti treatment, method for inhibiting nk cell activity in an individual, kit for predicting a cancer patient's responsiveness to fti treatment

摘要

The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods for treating an individual with a farnesyltransferase (fti) inhibitor which includes determining whether the individual is likely to respond to fti treatment based on the genotyping and expression profile of certain immunological genes and the status mutation ras of the individual.