首页> 外国专利> Biological analysis method for antibody against thyroid stimulating hormone receptor, measurement kit for antibody, and genetically modified cell modified for use in the biological analysis method or in the measurement kit

Biological analysis method for antibody against thyroid stimulating hormone receptor, measurement kit for antibody, and genetically modified cell modified for use in the biological analysis method or in the measurement kit

机译:抗甲状腺刺激激素受体抗体的生物学分析方法,抗体测定试剂盒以及用于该生物学分析方法或测定试剂盒中的转基因细胞

摘要

The present invention provides a method and a kit for assaying a TSH receptor antibody, which are easy to manipulate and are safe. Specifically, the present invention provides a composition comprising a genetically modified cell forced to co-express a TSH receptor, a cyclic nucleotide responsive calcium channel, and a luminescent protein aequorin. Use of the composition enables the assay of a TSH receptor antibody contained in a sample.
机译:本发明提供了易于操作且安全的用于测定TSH受体抗体的方法和试剂盒。具体地,本发明提供了一种组合物,其包含被迫共同表达TSH受体的基因修饰细胞,环状核苷酸响应性钙通道和发光蛋白水母发光蛋白。该组合物的使用使得能够测定样品中包含的TSH受体抗体。

著录项

  • 公开/公告号ES2642262T3

    专利类型

  • 公开/公告日2017-11-16

    原文格式PDF

  • 申请/专利权人 OTSUKA PHARMACEUTICAL CO. LTD.;

    申请/专利号ES20140195873T

  • 发明设计人 ARAKI NAOHIRO;

    申请日2010-06-24

  • 分类号C12N5;C12N5/10;C12N15/09;C12Q1/02;G01N33/50;G01N33/554;G01N33/68;G01N33/76;

  • 国家 ES

  • 入库时间 2022-08-21 12:48:49

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