1 1 Formulation composition of once-daily fixed-dose combination bilayer tablets of cilostazol and clopidogrel and manufacturing method thereof

摘要

The present invention relates to a once-daily twice-daily oral double-layer tablet containing a fixed dose of cilostazol and clopidogrel, and a method for preparing the same, wherein the two-layer tablet comprises a cilostazol emulsion layer and a clopidogrel emitter layer, Because the starzole emissive layer can contain a fixed amount of cilostazol and clopidogrel by including certain amounts of polyethylene oxide and Eudragit RS as the release agent, it is possible to provide a two-layered tablet that can be taken orally once a day, It can be widely used as an aged personalized preparation in which vascular diseases are frequently caused.