首页> 外国专利> A composition for use in the treatment or prevention of viral or bacterial infections in a subject undergoing antitumor chemotherapy, leukemia treatment or AIDS treatment, comprising l.reuteri ler03 and / or l.salivarius ls06

A composition for use in the treatment or prevention of viral or bacterial infections in a subject undergoing antitumor chemotherapy, leukemia treatment or AIDS treatment, comprising l.reuteri ler03 and / or l.salivarius ls06

机译:一种用于在接受抗肿瘤化学疗法,白血病治疗或AIDS治疗的受试者中用于治疗或预防病毒或细菌感染的组合物,其包含罗伊氏乳杆菌ler03和/或唾液乳杆菌ls06。

摘要

A composition for use as adjunctive therapy to antitumor chemotherapeutic treatments, acquired immunodeficiency syndrome treatments and leukemia treatments is described. The composition includes a strain of bacteria Lactobacillus reuteri LRE 03 DSM 23879 which is able to strongly stimulate the production of pro-inflammatory cytokines (Th1) interferon INF-gamma, the cytokines exhibiting a marked antiviral and/or antibacterial activity, and/or a bacterial strain Lactobacillus salivarius LS06 DSM 26037 which is able to strongly stimulate dendritic cell production, the dendritic cells exhibiting a marked antiviral and/or antibacterial activity. The composition can include one or more of: a bacterial strain able to produce, when ingested, bacterial exopolysaccharides EPS; and/or a plant polysaccharide such as tara gum; and/or an Aloe arborescens gel; and/or a gelling agent such as sodium alginate and/or a highly bioavailable zinc internalized into a tyndallized bacterial cell.
机译:描述了用作抗肿瘤化学治疗,获得性免疫缺陷综合症治疗和白血病治疗的辅助治疗的组合物。该组合物包括能强烈刺激促炎性细胞因子(Th1)干扰素INF-γ产生的罗伊氏乳杆菌LRE 03 DSM 23879菌株,该细胞因子显示出显着的抗病毒和/或抗菌活性,和/或细菌菌株唾液乳杆菌LS06 DSM 26037,其能够强烈刺激树突状细胞的产生,该树突状细胞表现出显着的抗病毒和/或抗菌活性。该组合物可以包括一种或多种:当被摄入时能够产生细菌胞外多糖EPS的细菌菌株;和和/或植物多糖如塔拉胶;和/或芦荟树胶;和/或胶凝剂(例如海藻酸钠)和/或内化到扁桃体化细菌细胞中的高生物利用度锌。

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