COMBINATION THERAPY FOR TREATING HEMORRHAGIC SHOCK

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine and a method of treating hemorrhagic shock or massive blood loss in mammals, which comprises administering tranexamic acid to a mammal in the amount between 0.005 and 0.5 g/kg of the body weight in combination with recombinant full-size SERPING1 or its serpin domain in the amount of 10 to 900 IU/kg of the body weight.;EFFECT: invention provides a significant reduction of mortality caused by hemorrhagic shock or massive blood loss.;6 cl, 8 ex, 10 dwg, 4 tbl