method for treating a dopamine deficiency disorder, method for improving active motor time without dyskinesia in a patient with parkinson's disease, method for reducing dyskinesia in an individual with a dopamine deficiency disorder, method for reducing inactive motor time in an individual with a dopamine deficiency disorder, method for reducing striatal dopamine level fluctuations in an individual with a dopamine deficiency disorder, method for reducing dyskinesia in an individual with a dopamine deficiency disorder after long-term treatment, pharmaceutical composition and packaging

摘要

The present invention relates to novel treatment combinations for abnormal dopamine deficiency disorders, and related conditions, comprising deuterated catecholamine derivatives and catechol-o-methyl transferase (comt) inhibitors.