methods for producing a hepatitis b vaccine and hepatitis b surface antigen.

摘要

"methods for producing a hepatitis b vaccine of a hepatitis b surface antigen for treatment and / or prophylaxis of hepatitis b virus infections, vaccine composition, use of a hepatitis b surface antigen, hepatitis immunogenic antigen" be vaccine ". The present invention relates to a method for producing a hepatitis b antigen suitable for use in a vaccine, the method comprising purifying the antigen in the presence of cysteine, for vaccines comprising such antigens.