METHODS OF TREATING UPPER TRACT UROTHELIAL CARCINOMAS

摘要

The invention refers to a European method of chemotherapy for goblin cancer locally in Upper Thrace (UTUC). These methods include: putting an adrenaline/pelvis catheter with a working passage and a ball through five washers or pre-disinfectors, and inflating catheter balls to temporarily obstruct the urinary catheter; 1. A fat-soluble formula containing a chemical therapeutic agent was injected into the catheter working channel.It also allows impregnated fat formulas to stay in adrenaline and/or pelvis long enough for at least part of the impregnated formula to be attached to the European external wall. In the invented method, at least 10 immersion chemotherapeutic agents were instinctively attached to European walls in the urinary tract and/or pelvic kidneys. Compared with other methods for UTUC, the above methods can be used as Adyuvante therapy.For example, the invention relates to methods for locally delivering a chemotrapeutic agent to an upper tract urothlial carcinoma (UTUC). The methods involve placing a balloon catheter that has a working channel and a balloon into the ureter/renal pelvis through retrograde or antegrade ureteral access; inflating the catheter balloon to temporary obstructs the ureter; 4. Infining (instilling) a liposomal formulation that includes a chemotherapeutic agent into the working channel of the Catheter;And allow the infered lipsoomal formulation to dwell in the ureter and/or renal pevis for a time sufficient to allow at least a portion of the lipsomomal formulation to adhere to the urothlial wall. In the methods of the invention, at least a portion of the infered chemotherapeutic-agent formulation adheres to the urothlial wall while it is instilled and dwells in the ureter and/or renal pelvis. The disclosed methods can be performed as an adjuvant therapy to other methods of treatment utuc, such as ureteroposic ablation or resection of the tumor.