N-ACYLATED HYALURONIC ACID FOR HYPERURICEMIA AND GOUTY ARTHRITIS

摘要

The invention provides a pharmaceutical composition of hyaluronic acid comprising repeating units of a disaccharide comprising glucuronic acid and N-acetylglucosamine, wherein a portion of the N-acetyl groups of the N-acetylglucosamine have been independently replaced with a group of the formula -N-C(O)-(C2-C4)-alkyl for treating hyperuricemia and gouty arthritis. Studies show that this composition is promising as an anti-gout therapeutic agent, which combines both anti-inflammatory actions as well as anti uracemic effects.