Hyaluronic Acid-Gold Nanoparticle-Tocilizumab Complex for the Treatment of Rheumatoid Arthritis

摘要

HA-AuNP-TCZ complex was successfully synthesized for the treatment of RA. The formation of HA-AuNP-TCZ complex was clearly confirmed by UV-vis spectra, TEM, and DLS analyses. Currently, the therapeutic effect of the complex on RA is investigated, which will corroborate the feasibility of HA-AuNP-TCZ complex for further development. The novel platform of HA-AuNP-antibody complex can be exploited for various therapeutic applications.