首页> 外国专利> A composition comprising an exosome derived from adipose-derived stem cell as an active ingredient and its application for improving dermatitis

A composition comprising an exosome derived from adipose-derived stem cell as an active ingredient and its application for improving dermatitis

机译:包含源自脂肪干细胞的外来体作为有效成分的组合物及其在改善皮炎中的应用

摘要

The present invention provides a composition for preventing, improving, relieving or treating dermatitis which comprises an adipose stem cell originated exosome as an active ingredient. A composition of the present invention acts on multiple cytokine targets which cause dermatitis, and thus widespread application with respect to dermatitis which is result from various causes is possible and dermatitis can be effectively controlled and relieved. Additionally, a composition of the present invention reduces moisture evaporation of a horny layer and improves skin moisturizing to protect and strengthen a skin barrier. Dermatitis can be prevented, improved, relieved or treated through protecting and strengthening a skin barrier. In detail, a composition of the present invention can control cytokine targets which show different expression aspects according to progression of disease of a mild, moderate or serious case, and thus a composition can be applied to prevent, improve, relieve or treat dermatitis of a mild, moderate or serious case. Moreover, cytokine targets which show different expression aspects according to a dermatitis occurring aspect of an acute or chronic case, and thus a composition can be applied to prevent, improve, relieve or treat dermatitis of an acute or chronic case.
机译:本发明提供了用于预防,改善,缓解或治疗皮炎的组合物,其包含源自脂肪干细胞的外来体作为活性成分。本发明的组合物作用于引起皮炎的多种细胞因子靶标,因此由各种原因引起的针对皮炎的广泛应用是可能的,并且可以有效地控制和缓解皮炎。另外,本发明的组合物减少了角质层的水分蒸发并改善了皮肤保湿性以保护和增强皮肤屏障。通过保护和加强皮肤屏障可以预防,改善,缓解或治疗皮肤炎。详细地,本发明的组合物可以根据轻度,中度或严重病例的疾病进展来控制表现出不同表达方面的细胞因子靶标,因此,该组合物可以用于预防,改善,缓解或治疗糖尿病的皮炎。轻度,中度或严重的情况。此外,根据急性或慢性病例的皮炎发生方面显示不同表达方面的细胞因子靶标,因此可以将组合物用于预防,改善,缓解或治疗急性或慢性病例的皮炎。

著录项

  • 公开/公告号KR20190003383A

    专利类型

  • 公开/公告日2019-01-09

    原文格式PDF

  • 申请/专利权人 EXOCOBIO INC.;

    申请/专利号KR20180074383

  • 发明设计人 YI YONG WEON;CHO BYONG SEUNG;

    申请日2018-06-27

  • 分类号A61K35/28;A23L33/10;A61K8/98;A61Q19;

  • 国家 KR

  • 入库时间 2022-08-21 11:51:53

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