首页> 外国专利> A composition comprising an exosome derived from adipose-derived stem cell as an active ingredient and its application for improving dermatitis

A composition comprising an exosome derived from adipose-derived stem cell as an active ingredient and its application for improving dermatitis

机译:包含源自脂肪干细胞的外来体作为有效成分的组合物及其在改善皮炎中的应用

摘要

The present invention provides a composition for the prevention, improvement, alleviation or treatment of dermatitis, comprising an exosome derived from adipose stem cells as an active ingredient. The composition of the present invention acts on multiple cytokine targets that cause dermatitis to enable a wide range of applications for dermatitis due to various causes and to effectively inhibit and alleviate dermatitis. In addition, the composition of the present invention can reduce and evaporate the stratum corneum and improve skin moisturization to protect and enhance the skin barrier, and can prevent, improve, alleviate or treat dermatitis through the protection and strengthening of the skin barrier. In particular, the composition of the present invention can control cytokine targets with different manifestations according to the degree of mild, moderate, and severe disease progression of dermatitis, and thus can be applied to the prevention, improvement, alleviation, or treatment of mild, moderate, or severe dermatitis. In addition, it is possible to control cytokine targets with different expression patterns according to the onset of dermatitis such as acute and chronic, so that it can be applied to the prevention, improvement, alleviation or treatment of acute and chronic dermatitis.
机译:本发明提供了用于预防,改善,减轻或治疗皮炎的组合物,其包含源自脂肪干细胞的外来体作为活性成分。本发明的组合物作用于引起皮炎的多种细胞因子靶标,由于各种原因使皮炎的广泛应用成为可能,并有效地抑制和减轻了皮炎。另外,本发明的组合物可以减少和蒸发角质层并改善皮肤保湿以保护和增强皮肤屏障,并且可以通过保护和增强皮肤屏障来预防,改善,减轻或治疗皮炎。特别地,本发明的组合物可以根据皮炎的轻度,中度和重度疾病进展的程度来控制具有不同表现形式的细胞因子靶标,因此可以用于预防,改善,缓解或治疗轻度,中度或严重的皮炎。另外,可以根据诸如急性和慢性的皮炎的发作控制具有不同表达模式的细胞因子靶标,从而可以将其应用于预防,改善,减轻或治疗急性和慢性皮炎。

著录项

  • 公开/公告号KR102045188B1

    专利类型

  • 公开/公告日2019-11-14

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20180074383

  • 发明设计人 이용원;조병성;

    申请日2018-06-27

  • 分类号A61K35/28;A23L33/10;A61K8/98;A61Q19;

  • 国家 KR

  • 入库时间 2022-08-21 11:08:29

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