KP1 Novel Klebsiella genus bacteria specific bacteriophage KP1 and antibacterial composition comprising the same

摘要

The present invention relates to a novel bacteriophage KP1 having killing activity specific to a bacterium belonging to the genus Klebsiella, particularly an extended-spectrum beta-lactamase ( Klebsiella ) bacterium, a Klebsiella bacterium comprising the bacteriophage A method for preventing or treating an infectious disease caused by Klebsiella, which comprises the step of administering to a subject a pharmaceutical composition, antibiotic composition, feed additive composition, feed, disinfectant or detergent for preventing or treating infectious diseases caused by infectious diseases . The method for preventing or treating infectious diseases caused by Klebsiella spp. Using the bacteriophage KP1 of the present invention is more specific than the conventional antibiotics such as Klebsiella spp., Especially ESBL-Klebsiella spp. And the bacteriophage KP1 has an advantage of being excellent in physicochemical stimulation by exhibiting excellent lytic activity by infection with Klebsiella spp. In addition, since the bacteriophage KP1 of the present invention is not infected with any host other than a bacterium such as a human, an animal, or a plant, it has an advantage of being able to solve problems of antibiotic resistant bacteria caused by abuse of antibiotics, have. Accordingly, the bacteriophage KP1 of the present invention can be used in various fields in the field of preventing or treating infectious diseases caused by Klebsiella spp., Antibiotic composition, composition for feed addition, feed, disinfectant, or detergent.