Apparatus for cultivating and radiation-induced killing of living biological cells, uses of the apparatus, and methods for studying migration and / or wound healing of biological cells

摘要

A device is provided which is suitable for culturing and radiation-induced killing of living biological cells. The device contains a planar substrate and a functional layer applied to the planar substrate for wounding biological cells. The functional layer contains at least one photosensitizer which is suitable for converting triplet oxygen into singlet oxygen by the action of electromagnetic radiation. This causes biological cells on the functional layer can be killed by irradiation of low-intensity electromagnetic radiation. It can be easily, quickly, gently, flexibly and inexpensively introduced into a cell layer at a locally defined location a wound and wound healing to be studied. Uses of the devices and a method for studying migration and / or wound healing of biological cells are presented.