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METHOD FOR ASSISTING DETERMINATION OF HEMATOLOGICAL STAGE OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA
METHOD FOR ASSISTING DETERMINATION OF HEMATOLOGICAL STAGE OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA
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机译:确定儿童急性淋巴细胞性白血病的血液学阶段的方法
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摘要
Provided are a method for assisting in determining the hematological stage of childhood acute lymphoblastic leukemia (child ALL), and an in-vitro diagnostic pharmaceutical product usable in the method. The method for assisting in determining the hematological stage of child ALL comprises the steps of (1) obtaining the mRNA level of Wilms' tumor-1 gene (WT1) in at least one of the biological samples of peripheral blood and bone marrow fluid from a test subject; (2) obtaining the GAPDH mRNA level in the biological sample; and (3) calculating an index value necessary for assisting in the determination based on the ratio of the WT1 mRNA level obtained in step (1) to the GAPDH mRNA level obtained in step (2).
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