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METHOD FOR PREDICTING EFFECT OF TUMOR IMMUNOTHERAPY USING TUMOR CYTOTOXIC ACTIVITY OF PERIPHERAL BLOOD T CELLS AS INDEX
METHOD FOR PREDICTING EFFECT OF TUMOR IMMUNOTHERAPY USING TUMOR CYTOTOXIC ACTIVITY OF PERIPHERAL BLOOD T CELLS AS INDEX
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机译:以外周血T细胞的肿瘤细胞毒活性为指标的肿瘤免疫治疗效果预测方法
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摘要
An object of the present invention is to provide a companion diagnostic for predicting the effect of a tumor immunotherapy. The effect of a tumor immunotherapy is predicted by a method including step 1: contacting directly or indirectly peripheral blood mononuclear cells collected from a patient who is a target for treatment of a malignant tumor with tumor cells in vitro; step 2: determining whether the tumor cells that contacted with the peripheral blood mononuclear cells in step 1 are damaged; and step 3: determining that the tumor immunotherapy is effective against the malignant tumor in the patient when the tumor cells are determined to have been damaged in step 2.
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