FEED FOR NON-ALCOHOLIC STEATOHEPATITIS-INDUCED EXPERIMENTAL ANIMAL AND METHOD FOR PRODUCING THE SAME, AND METHOD FOR MAKING NON-ALCOHOLIC STEATOHEPATITIS MODEL ANIMALS

摘要

To provide feed for producing, without using genetic defects or drugs, NASH-induced experimental animals that show a pathological condition closer to that of NASH, the feed being a feed for NASH-induced experimental animal which does not affect the growth of experimental animals, to provide methods for producing the same and to provide methods for making NASH model animals.SOLUTION: Non-alcoholic steatohepatitis-induced experimental animal feed containing 35-60 mass% of carbohydrate source, 10-25 mass% of amino acid source, 15-35 mass% of fats and oils, and 3-8 mass% of minerals and/or metal salts, contains (i) 0.05 to 0.4 mass% of methionine as the amino acid source, (ii) 0.01 mass% or less of cholines, and (iii) 0.05 to 0.5 mass% of an iron compound as the minerals and/or metal salts. There are also provided a method for producing the same and a method for producing non-alcoholic steatohepatitis model animals.SELECTED DRAWING: None