Identification of microorganisms from genome sequencing data

摘要

A diagnostic analysis method and system is provided for identifying a microorganism from a genome sequence. Partially or fully assembled microbial genomes or short reads from whole-genome sequencing of microbial genomes are processed into a 4 MB Boolean array while preserving 1% of the genomic information in a way that allows for rapid comparison of a query genome to a large reference database. This represents a critical savings in storage space and speed by which large reference libraries can be queried.