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METHOD OF TREATING FATTY ACID OXIDATION DISORDERS USING OMEGA3/OMEGA6 UNSATURATED OR BRANCHED CHAIN FATTY ACIDS
METHOD OF TREATING FATTY ACID OXIDATION DISORDERS USING OMEGA3/OMEGA6 UNSATURATED OR BRANCHED CHAIN FATTY ACIDS
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机译:使用OMEGA3 / OMEGA6未饱和或支链脂肪酸的脂肪酸处理脂肪酸氧化紊乱的方法
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摘要
A method of treating medium chain acyl-CoA dehydrogenase deficiency, very long chain acyl-CoA dehydrogenase deficiency, long chain hydroxyacyl-CoA dehydrogenase deficiency, trifunctional protein deficiency, or CPT II deficiency in a patient is provided comprising administering to the patient a therapeutic amount of a triglyceride or other conjugated fatty acid that bypasses or leads to an intermediate that bypasses the deficient enzyme. Amino acid-conjugated fatty acids also are provided as well as compositions comprising the amino acid-conjugated fatty acids.
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