compound or a salt thereof, prodrug, drug, fatty acid amide hydrolase inhibitor, use of the compound or prodrug, fatty acid amide hydrolase inhibition methods in a mammal, brain cell protection and / or neural cells in a mammal to prevent or treat cerebrovascular disorders, head injury or spinal cord damage in a mammal, to prevent or treat disease, to protect brain cells and / or neural cells in a mammal, of Measuring a Fatty Acid Amide Hydrolase Activity and Preventing or Treating Sleep Disorders in a Mammal, Brain-Neuroprotective and Therapeutic or Prophylactic Agents, Kit, and Process for Producing a Compound

摘要

COMPOUND OR A SALT OF THE SAME, PRODUCT, MEDICINAL PRODUCT, FATTY ACID AMIDE HYDROLASE INHIBITOR, USE OF COMPOUND OR PRODUCT, FATTY ACID AMIDE HYDROLASE METHODS, IN A PROPHYAL CULA MAMMIFER, AND / OR NEURAL CELLS IN A MAMMALIAN, FOR PREVENTION OR TREATMENT OF CEREVOVASCULAR DISORDERS, HEAD INJURY OR SPINAL CORD DAMAGE, FOR PREVENTION OR TREATMENT OF CELL AND NEEDLE / CELL IN THE CELL MEASUREMENT OF A FATTY ACID AMIDE HYDROLASE ACTIVITY OR A FATTY ACID AMIDE HYDROLASE ACTIVITY AND PREDICTION OR TREATMENT OF SLEEP DISORDERS IN A MAMMALIAN, PROTEPHERE, PROTECT, AND NEUTROPROETE PROTETETIC, BRAIN NEUROLASE ACTIVITY TO PRODUCE A COMPOUND. A FAAH inhibitor, and a preventive / therapeutic agent for cerebrovascular disorders and a preventive / therapeutic agent for sleep disorders, each containing the inhibitor. The FAAH inhibitor is a compound represented by the formula (I-O ~ '): (wherein Z represents oxygen or sulfur; R¬1¬ represents optionally substituted aryl or an optionally substituted heterocyclic group; R¬1a¬ represents h, or an optionally substituted hydrocarbon group, hydroxy, etc. R 1 represents optionally substituted piperidine-1,4-diyl or optionally substituted piperazine-1,4-diyl R 3 represents an optionally substituted group formed by removal of two atoms of a 5-membered aromatic heterocycle having from 1 to 3 heteroatoms selected from nitrogen, oxygen, and sulfur, or represents -CO-, etc., and R¬ 4¬ represents an optionally substituted hydrocarbon group or optionally substituted heterocyclic group) or a salt of the compound.