首页>
外国专利>
NON-INVASIVE URINARY BIOMARKERS FOR THE DETECTION OF UROTHELIAL CARCINOMA OF THE BLADDER
NON-INVASIVE URINARY BIOMARKERS FOR THE DETECTION OF UROTHELIAL CARCINOMA OF THE BLADDER
展开▼
机译:检测膀胱尿路上皮癌的非侵袭性尿液生物标志物
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods for detecting urothelial carcinomas. In one embodiment, a method comprises the step of detecting CD24, CD49f and NANOG in a urine sample obtained from a patient suspected of having urothelial carcinoma. In a specific embodiment, the detection step comprises polymerase chain reaction (PCR). In certain embodiment, the PCR step utilizes at least one primer comprising SEQ ID NOS: 1, 2, 23, 24, 13 and 14. In another embodiment, the method further comprises treating the patient with one or more of surgery, radiation therapy, chemotherapy and immunotherapy.
展开▼
机译:本发明涉及癌症领域。更具体地,本发明提供了用于检测尿路上皮癌的组合物和方法。在一个实施方案中,一种方法包括以下步骤:检测从怀疑患有尿路上皮癌的患者获得的尿液样品中的CD24,CD49f和NANOG。在一个具体的实施方案中,检测步骤包括聚合酶链反应(PCR)。在某些实施方案中,PCR步骤利用至少一种包含SEQ ID NOS:1、2、23、24、13和14的引物。在另一实施方案中,该方法进一步包括用外科手术,放射疗法,化学疗法和免疫疗法。
展开▼