2.5 PM2.5 Biomarkers for identification of inflammatory response-related genes under exposure to particulate matterPM 2.5 using human vascular endothelial cell line and the method using the same

摘要

The present invention relates to a biomarker for confirming whether the inflammatory response-related gene expression according to the exposure of fine dust (PM2.5) or less than 2.5 micrometers and a method of identifying the same using the same, and more specifically 2.5 micrometers using human vascular endothelial cells. Hereinafter, the present invention relates to a biomarker related to an inflammatory response specifically changed by PM2.5 exposure and a method of confirming whether or not to expose PM2.5 below 2.5 micrometers using the same. The present invention is to determine whether the inflammatory response related gene expression in vascular endothelial cells including an inflammatory response-related biomarker (or microarray chip) showing a specific expression change by exposure to fine dust (PM2.5) or less than 2.5 micrometers Through the kit and the method of checking the exposure of the fine dust (PM2.5) of less than 2.5 micrometers using the same, it can be usefully used to monitor the exposure and risks of the fine dust of less than 2.5 micrometers (PM2.5).