首页> 中国专利> 一种药物在制备治疗脑转移瘤及其相关疾病的药品中的应用

一种药物在制备治疗脑转移瘤及其相关疾病的药品中的应用

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摘要

本申请提供一种药物在制备治疗脑转移瘤相关疾病的药品中的应用，其中，所述药物包括能够促进TRPV4信号通道的钙离子内流的至少一种TRPV4激动剂，所述脑转移瘤及其相关疾病包括脑转移瘤、脑转移瘤形成过程中产生的疾病以及脑转移瘤引起的并发症、后遗症、与脑转移瘤具有相关性的疾病。将上述药物应用于制备治疗脑转移瘤相关疾病的药品中，可以通过明确的作用机制起到显著的抗肿瘤作用，治疗效果佳，应用前景好。

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公开/公告号CN111773390B

专利类型发明专利
公开/公告日2021-08-20

原文格式PDF
申请/专利权人南京大学;
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申请/专利号CN202010622510.8
发明设计人闫超;黄腾飞;徐天琦;
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申请日2020-07-01
分类号A61K45/06(20060101);A61K31/05(20060101);A61K31/4188(20060101);A61K31/045(20060101);A61P35/04(20060101);A61P1/08(20060101);A61P39/00(20060101);
代理机构11810 北京智丞瀚方知识产权代理有限公司;
代理人白月霞
地址 210046 江苏省南京市栖霞区仙林大道163号
入库时间 2022-08-23 12:20:07

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1. 一种药物在制备治疗脑转移瘤及其相关疾病的药品中的应用 [P] . 中国专利： CN111773390B . 2021.08.20
2. 一种免疫抑制药物及中亚苦蒿提取物在制备治疗自身免疫相关疾病的药物中的应用 [P] . 中国专利： CN112089743A . 2020-12-18
3. PEPTIDE, PEGUILLED PEPTIDE, COMPOSITION, PHARMACEUTICAL COMPOSITION, BOTTLE, DISINFECTION SOLUTION, METHOD FOR GROWTH INHIBITION, REPLICATION OR INFECTIVITY OF A MICRO-ORGANISM, METHOD FOR INHIBITION OF A BACTERIAL GROWTH, BACTERIAL GROWTH INHIBITION, TREATMENT OF A MICRO-ORGANISM INFECTION IN A SUBJECT AND PREVENTION OF A DISEASE IN A SUBJECT CAUSED BY OR ASSOCIATED WITH A MICRO-ORGANISM INFECTION, METHOD FOR INHIBITING BACTERIAL GROWTH IN A SUBJECT, A METHOD OF TREATMENT OF A BACTERIAL TREATMENT SUBJECT AND TREATMENT OF A DISEASE CAUSED BY OR ASSOCIATED WITH A BACTERIAL INFECTION, METHOD FOR PREVENTING A DISEASE CAUSED BY OR ASSOCIATED WITH A BACTERIAL INFECTION IN A SUBJECT, METHOD FOR INHIBITION OF VIRAL REPLICATION IN A SUBJECT TO A SUBJECT TO A SUBJECT ON A SUBJECT AND TREATMENT OF A DISEASE CAUSED BY OR ASSOCIATED WITH A VIRAL INFECTION IN A SUBJECT, METHOD FOR THE PREVENTION OF A DISEASE CAUSED BY OR ASSOCIATED WITH A VIRAL INFECTION IN A SUBJECT, METHOD FOR DISINFECTING AN INA [P] . BR112017028190A2 . 2018-09-04

机译：肽，规定的肽，成分，药物成分，瓶，消毒溶液，微生物的生长抑制，复制或感染的方法，细菌生长的抑制方法，细菌生长的抑制作用，治疗由微生物感染引起或与之有关的疾病的预防，疾病的抑制方法，一种细菌治疗方法的治疗和一种或多种细菌引起的疾病的治疗感染，预防由细菌感染引起的疾病或与之相关的疾病的方法，在受试者体内抑制病毒复制的方法以及对由细菌引起或与之相关的疾病的治疗在主题中，一种预防由对象中的病毒感染引起或与之相关的疾病的方法，一种用于对INA进行消毒的方法
4. composition, pharmaceutical composition, effervescent dosage form, multiple unit oral oral pharmaceutical composition, extended release pharmaceutical dosage form, enteric coated pharmaceutical dosage form, stable pharmaceutical dosage form for oral administration to mammalian subjects, method for treating diseases acid-related diseases by inhibiting gastric acid secretion, method for treating a bacterial infection caused or caused by helicobacter pylori, process for preparing a compound of formula 3, process for preparing a compound of formula 5, use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion, use of a compound of formula 1 for the preparation of a medicament for treating a bacterial infection caused or caused by helicobacter pyl or use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion [P] . BRPI0617987A2 . 2011-08-16

机译：组合物，药物组合物，泡腾剂型，多单位口服口服药物组合物，缓释药物剂型，肠溶衣药物剂型，向哺乳动物受试者口服给药的稳定药物剂型，通过抑制胃酸治疗疾病的方法酸分泌，治疗由幽门螺杆菌引起或引起的细菌感染的方法，制备式3化合物的方法，制备式5化合物的方法，式1化合物在制备用于治疗胃的药物中的用途通过抑制胃酸分泌来治疗与酸有关的疾病，将式1的化合物用于制备用于治疗由幽门螺杆菌引起或引起的细菌感染的药物，或将式1的化合物用于制备用于治疗的药物通过抑制胃酸分泌来治疗胃酸相关疾病
5. compound, pharmaceutical composition, methods for treating an estrogen-related disorder and cancer, for manufacturing a medicament for therapeutic use in the treatment of a disorder, and for preventing an estrogen-related disorder, use of a compound or composition and process for preparing a pharmaceutical product. [P] . BR112018011607A2 . 2018-11-27

机译：化合物，药物组合物，治疗雌激素相关疾病和癌症的方法，制造用于治疗该疾病的药物以及预防雌激素相关疾病的药物，该化合物或组合物的用途和制备方法药品。