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6-姜酚在制备治疗和预防前列腺癌及抗前列腺癌转移药物的用途

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摘要

本发明属于生物医药技术领域，具体涉及一种6‑姜酚在制备治疗和预防前列腺癌及抗前列腺癌转移药物的用途。6‑姜酚能够有效抑制雄性素依赖型前列腺癌与非雄性素依赖型前列腺癌细胞的增殖及抗癌转移作用，具有良好效果；6‑姜酚还能能够降低现有药物治疗前列腺癌的副作用。

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公开/公告号CN113546065A

专利类型发明专利
公开/公告日2021-10-26

原文格式PDF
申请/专利权人宜春学院;
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申请/专利号CN202111043745.2
发明设计人刘棋铭;安丽杰;陈卫东;
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申请日2021-09-07
分类号A61K31/12(20060101);A61K31/337(20060101);A61K36/9068(20060101);A61P13/08(20060101);A61P35/00(20060101);A61P35/04(20060101);A61K125/00(20060101);
代理机构61223 西安铭泽知识产权代理事务所(普通合伙);
代理人崔瑞迎
地址 336099 江西省宜春市袁州区学府路576号
入库时间 2023-06-19 13:02:24

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1. 6-姜酚在制备治疗和预防前列腺癌及抗前列腺癌转移药物的用途 [P] . 中国专利： CN113546065A . 2021-10-26
2. miR-204-5p在制备NF-κB抑制剂及前列腺癌转移预防和治疗中的应用 [P] . 中国专利： CN108938660A . 2018-12-07
3. phosphodiesterase 4d7 (pde4d7), for use as a marker for hormone-sensitive malignant prostate cancer; composition or method of data acquisition or immunoassay to diagnose, detect, monitor or predict hormone-sensitive malignant prostate cancer or to diagnose, detect, monitor or predict progression to hormone-sensitive malignant prostate cancer; use of pde4d7; immunoassay to discriminate between a benign prostate tumor and a hormone-sensitive malignant prostate cancer; method for identifying an individual for eligibility for hormone-sensitive malignant prostate cancer therapy; immunoassay to classify an individual or section of individuals with a hormone-sensitive malignant prostate cancer disease; inhibitory pharmaceutical composition for the treatment or prevention of hormone sensitive malignant prostate cancer; stimulatory pharmaceutical composition; and; use of a pde4d7 protein-specific antibody and / or a pde4d7 protein-specific antibody variant [P] . BRPI1007704A2 . 2019-12-03

机译：磷酸二酯酶4d7（pde4d7），用作激素敏感性恶性前列腺癌的标志物;用于诊断，检测，监测或预测激素敏感性恶性前列腺癌或诊断，检测，监测或预测进展为激素敏感性恶性前列腺癌的数据采集或免疫测定的组合物或方法;使用pde4d7;免疫测定，以区分良性前列腺肿瘤和激素敏感性恶性前列腺癌;鉴定有资格接受激素敏感性恶性前列腺癌治疗的人的方法;免疫测定法，对患有激素敏感性恶性前列腺癌的个体或个体进行分类;用于治疗或预防激素敏感性恶性前列腺癌的抑制性药物组合物;刺激性药物组合物;和; pde4d7蛋白特异性抗体和/或pde4d7蛋白特异性抗体变异的用途
4. Medicament for prevention of prostate cancer development or for prevention or treatment of prostate cancer metastases in marrow [P] . CZ287977B6 . 2001-03-14

机译：预防前列腺癌发展或预防或治疗骨髓中前列腺癌转移的药物
5. methods for determining prostate cancer susceptibility in a human individual, identifying a marker for use in prostate cancer susceptibility assessment, and for genotyping a nucleic acid sample obtained from a human individual at risk of, or diagnosed with, cancer to assess a human individual for likelihood of response to a therapeutic agent to prevent and / or ameliorate symptoms associated with prostate cancer, to predict prognosis of an individual diagnosed with cancer, and to monitor progress in treatment of an individual undergoing treatment. for prostate cancer, kit for assessing susceptibility to prostate cancer in a human individual, use of a computer readable oligonucleotide probe, and apparatus for determining a genetic indicator for prostate cancer in a human individual. [P] . BRPI0807236A2 . 2019-09-24

机译：用于确定人类个体中前列腺癌易感性，鉴定用于前列腺癌易感性评估中的标记以及对从患有癌症或被诊断患有癌症的人类个体获得的核酸样品进行基因分型以评估人类个体可能性的方法对治疗剂的反应的预防，预防和/或改善与前列腺癌有关的症状，预测诊断为癌症的个体的预后以及监测正在接受治疗的个体的治疗进展。用于前列腺癌的试剂盒，用于评估人类个体对前列腺癌的易感性的试剂盒，计算机可读寡核苷酸探针的用途以及用于确定人类个体的前列腺癌的遗传指标的设备。