Validation of the Quadriphasic Mixture Theory for Intervertebral Disc Tissue

摘要

The selling and shrinking behavior of soft biological tissues is describes by aquadriphasic mixture model. In this model four phases are distinguished: a charged solid, a fluid, cations and anions. A description of the set of coupled differential equations of this quadriphasic mixture model is given. These equations are solved by the finite element method using a weighted residual approach. The resulting non-linear integral equations are linearized and solved by the Newton-Raphson iteration procedures. We performed some confined swelling and compression experiments on intervertebral disc tissue. These experiments are simulated by a one-dimensional finite element implementation of this quadriphasic mixture model.