From laparoscopic to open Kasai portoenterostomy: The outcome after reintroduction of open Kasai portoenterostomy in infant with biliary atresia

摘要

Purpose: Apparently superior result was observed after open Kasai portoenterostomy in infant with biliary atresia. Our institute stopped performing laparoscopic portoenterostomy since 2007. We aimed to investigate the outcome after reintroduction of open portoenterostomy. Methods: 27 non-syndromic infants underwent open Kasai portoenterostomy from 2007 to 2012. The age and the sex of the patient, the bilirubin level before the operation, the early clearance of jaundice (total bilirubin <20 μmol/L within 6 month of portoenterostomy), the native liver survival at 2 years after the operation were reviewed. The results were retrospectively compared with all 16 infants who underwent laparoscopic Kasai portoenterostomy before 2007. Results: All infants had type III biliary atresia. No statistical difference was observed regarding the age at operation and the pre-operative bilirubin level. The early clearance of jaundice rate was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation (p = 0.03). At 2 years after the operation, the native liver survival was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation (p = 0.03). Conclusion: Reintroduction of open Kasai portoenterostomy was associated with superior early clearance of jaundice rate and 2-year native liver survival rate.