Efficient synthesis of O-succinimidyl-(tert-butoxycarbonylamino)methyl carbamates derived from alpha-amino acids accelerated by ultrasound: Application to the synthesis of ureidodipeptides

摘要

The synthesis of O-succinimidyl-(tert-butoxycarbonylamino)methyl carbamates employing isocyanates made through the Curtius rearrangement of Boc-amino acid azides in the presence of N-hydroxysuccinimide under the influence of ultrasound is described.