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Left thoracic curve patterns and their association with disease.

机译:左胸曲线模式及其与疾病的关系。

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STUDY DESIGN: Analysis of clinical database material collected prospectively. OBJECTIVE: Examination of the association between lateralization of scoliotic curves and the existence of underlying disease. SUMMARY OF BACKGROUND DATA: It has been suggested that left thoracic scoliosis configurations are intrinsically pathologic, whereas the more usual right curve is, in a sense, "normal." METHODS: Research-based records were analyzed. Scoliosis configuration, patient gender, and diagnostic group were correlated. The results were interpreted within a biologic framework. RESULTS: Congenital and infantile idiopathic scoliosis showed a random right-left curve distribution. In older age groups, boys were more likely to have a left thoracic curve and to have underlying disease, but there was no association between the two. In girls, occurrence in childhood itself and left thoracic patterns within that group were associated with disease. Nevertheless, most curves were in the right thoracic pattern, regardless of cause. CONCLUSIONS: Although an association exists between left thoracic curves and disease, it is not strong enough to determine who should be intensively investigated, to the exclusion of other clinical findings, and it seems inappropriate for a different approach to be adopted on the basis of scoliosis pattern alone. Gender in males and age at occurrence in females are more important risk factors than in scoliosis configuration. All new cases of scoliosis treated by a physician warrant equally meticulous assessment, with more sophisticated investigative techniques where indicated by the complete clinical picture, of which curve lateralization is only a part. Biologic theories of left and right are more capable of dealing with the phenomenon of scoliosis lateralization than are simple mechanics or concepts of specific diseases.
机译:研究设计:前瞻性收集的临床数据库资料的分析。目的:检查脊柱侧弯曲线的侧向化与潜在疾病的存在之间的关系。背景数据总结:已经提出,左胸椎侧弯形态在本质上是病理性的,而从某种意义上来说,更常见的右弯是“正常的”。方法:分析基于研究的记录。脊柱侧弯形态,患者性别和诊断组相关。在生物学框架内解释了结果。结果:先天性和婴儿性特发性脊柱侧弯呈随机的左右曲线分布。在年龄较大的组中,男孩更有可能出现左胸曲线并患有基础疾病,但是两者之间没有关联。在女孩中,童年时期本身的发生和该组中左胸的形态与疾病有关。尽管如此,无论原因如何,大多数曲线都处于正确的胸腔形态。结论:尽管左胸曲线与疾病之间存在关联,但尚不足以确定应进行深入研究的人,而排除其他临床发现,并且基于脊柱侧弯采用其他方法似乎不合适。模式。与脊柱侧弯相比,男性的性别和女性的发病年龄更为重要。由医生治疗的所有新的脊柱侧弯病例都应进行同样细致的评估,并在完整的临床图片中指出采用更复杂的研究技术,其中曲线偏侧化只是其中一部分。与简单的机制或特定疾病的概念相比,左右生物学的理论更能应对脊柱侧弯现象。

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