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Is local bone viable as a source of bone graft in posterior lumbar interbody fusion?

机译:腰椎后路椎间融合术中局部骨是否可行作为骨移植的来源?

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STUDY DESIGN: Radiographic evaluation of bony union and clinical outcome were investigated after posterior lumbar interbody fusion (PLIF) performed with only local bone. OBJECTIVES: To examine the viability of local bone for bone graft in PLIF. SUMMARY OF BACKGROUND DATA: Different sources of bone graft have been used for PLIF. Autologous iliac bone is most likely suitable for biologic bone healing ability, but there may be some questions such as donor site pain. Allograft and artificial bones are less effective for bone healing. Use of local bone could be a solution. However, the quality of local bone is still being questioned and there is hesitation to use local bone alone. MATERIALS AND METHODS: Thirty-two patients underwent PLIF (24 single-level and 8 double-level) using the Brantigan I/F Carbon Cage filled with local bone and segmental pedicle screw fixation. At 3, 6, and 12 months after surgery, "parallel AP view radiograph" was obtained to evaluate bony union status. Average follow-up period was26 months. Clinical outcome was also evaluated by the Japanese Orthopedic Association clinical score. RESULTS: The bony union rate was 16.7%, 72.4%, and 100% at 3, 6, and 12 months after surgery, respectively. Clinically, the average of JOA scores was improved significantly (P < 0.001). The improvement rate was 72.9% (12 mo) and 76.8% (24 mo) on average. CONCLUSIONS: A 100% bony union rate was obtained 12 months after PLIF with only local bone. The results showed that clinical viability of local bone as a source of bone graft in PLIF.
机译:研究设计:仅对局部骨进行后路腰椎椎体间融合术(PLIF)后,对骨结合的放射学评价和临床结果进行了研究。目的:检查PLIF中用于植骨的局部骨的生存能力。背景数据摘要:PLIF使用了不同来源的骨移植物。自体骨最有可能适合生物学的骨愈合能力,但可能存在一些问题,例如供体部位疼痛。同种异体骨和人造骨对骨愈合的作用较小。使用局部骨骼可能是一种解决方案。然而,局部骨骼的质量仍然受到质疑,并且犹豫是否要单独使用局部骨骼。材料与方法:32例患者接受了Brantigan I / F碳钉笼(局部骨和节段椎弓根螺钉固定)的PLIF治疗(24级单层和8级双级)。在手术后的3、6和12个月,获得“平行AP查看X射线照片”以评估骨结合状态。平均随访期为26个月。还通过日本骨科协会临床评分评估了临床结局。结果:术后3、6和12个月的骨结合率分别为16.7%,72.4%和100%。临床上,JOA评分的平均水平显着提高(P <0.001)。平均改善率为72.9%(12个月)和76.8%(24个月)。结论:PLIF术后12个月仅局部骨性骨结合率达到100%。结果显示PLIF中作为骨移植物来源的局部骨的临床可行性。

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