Vitamin D prevents articular cartilage erosion by regulating collagen II turnover through TGF-beta 1 in ovariectomized rats

Li S.; Niu G.; Wu Y.; Du G.; Huang C.; Yin X.; Liu Z.; Song C.; Leng H.

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Vitamin D prevents articular cartilage erosion by regulating collagen II turnover through TGF-beta 1 in ovariectomized rats

机译：维生素D通过调节TGF-β1调节去卵巢大鼠的II型胶原代谢来防止关节软骨侵蚀

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Objective: To explore the effect of vitamin D on turnover of articular cartilage with ovariectomy (OVX) induced OA, and to investigate transforming growth factor-beta 1 (TGF-beta 1) as a possible underlying mechanism mediated by 1 alpha,25(OH)(2)D-3.

机译：目的：探讨卵巢切除术（OVX）诱发的OA中维生素D对关节软骨更新的影响，并探讨转化生长因子-β1（TGF-β1）作为1α，25（OH）介导的可能的潜在机制）（2）D-3。

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《Osteoarthritis and cartilage》 |2016年第2期|共9页
作者
Li S.; Niu G.; Wu Y.; Du G.; Huang C.; Yin X.; Liu Z.; Song C.; Leng H.;
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正文语种 eng
中图分类骨科学（运动系疾病、矫形外科学）;
关键词
Vitamin D; Articular cartilage degradation; CTX-II; TGF-beta 1; Ovariectomized rats; Chondrocytes;

机译：维生素D;关节软骨降解;CTX-II;TGF-beta 1;去卵巢大鼠;软骨细胞;

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专利

1. Vitamin D prevents articular cartilage erosion by regulating collagen II turnover through TGF-beta 1 in ovariectomized rats [J] . Li S., Niu G., Wu Y., Osteoarthritis and cartilage . 2016,第2期

机译：维生素D通过调节TGF-β1调节去卵巢大鼠的II型胶原代谢来防止关节软骨侵蚀
2. Alendronate protects against articular cartilage erosion by inhibiting subchondral bone loss in ovariectomized rats [J] . ZhuS., ChenK., LanY., Bone . 2013,第2期

机译：阿仑膦酸盐通过抑制去卵巢大鼠软骨下骨丢失来预防关节软骨侵蚀
3. Denaturation of type II collagen in articular cartilage in experimental murine arthritis. Evidence for collagen degradation in both reversible and irreversible cartilage damage. [J] . Stoop R, van der-Kraan-PM, Buma P, Journal of Pathology: Journal of the Pathological Society of Great Britain and Ireland . 1999,第3期

机译：实验性鼠关节炎的关节软骨中II型胶原的变性。可逆和不可逆软骨损伤中胶原蛋白降解的证据。
4. ENHANCING THE MECHANICAL PROPERTIES OF ARTICULAR CARTILAGE THROUGH ENZYME-MEDIATED COLLAGEN CROSSLINKING AS REGULATED BY LOW OXYGEN TENSION [C] . Eleftherios A. Makris, Jerry Hu, Kyriacos A. Athanasiou ASME summer bioengineering conference;SBC2012 . 2012

机译：通过低氧张力调节的酶介导的胶原蛋白交联增强关节软骨的机械性能
5. Design of an electrospun type II collagen scaffold for articular cartilage tissue engineering. [D] . Barnes, Catherine Pemble. 2007

机译：用于关节软骨组织工程的电纺II型胶原支架的设计。
6. Dangguijihwang-tang and Dangguijakyak-san Prevent Menopausal Symptoms and Dangguijihwang-tang Prevents Articular Cartilage Deterioration in Ovariectomized Obese Rats with Monoiodoacetate-Induced Osteoarthritis [O] . Hye Won Lee, Byung-Seob Ko, Suna Kang, 2017

机译：当归黄旺汤和当归黄芪散预防更年期症状当归吉黄汤预防单碘乙酸酯诱发的卵巢切除的肥胖大鼠的关节软骨恶化
7. Vitamin D prevents articular cartilage erosion by regulating collagen II turnover through TGF-β1 in ovariectomized rats [O] . S. Li, G. Niu, Y. Wu, 2016

机译：维生素D通过在卵巢切除大鼠中通过TGF-β1调节胶原II营业液来防止关节软骨侵蚀

Vitamin D prevents articular cartilage erosion by regulating collagen II turnover through TGF-beta 1 in ovariectomized rats

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