Consider a single intraoperative fraction for patients eligible for hypofractionated regimens?

摘要

Without a doubt, Eblan et al have provided an excellent review of the literature on use of hy-pofractionated whole breast irradiation (HF-WBI) regimens-discussing their rationale, associated controversies, available results, and ongoing research-in the context of conservative curative management of breast cancers. [1] The large randomized trials are well documented and described, with the authors highlighting differences in selection criteria that may sometimes explain the variations in reported outcomes. Overall, there is convincing evidence that, with a properly selected cohort of patients, HF-WBI will provide the same level of benefit as conventional WBI.