A Humanized Anti-Interleukin 6 Receptor Monoclonal Antibody, Tocilizumab, for the Treatment of Endometriosis in a Rat Model

Taskin Mine Islimye; Gungor Aysenur Cakir; Adali Ertan; Yay Arzu; Onder Gozde Ozge; Inceboz Umit

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A Humanized Anti-Interleukin 6 Receptor Monoclonal Antibody, Tocilizumab, for the Treatment of Endometriosis in a Rat Model

机译：人源化抗白介素6受体单克隆抗体Tocilizumab，用于治疗大鼠子宫内膜异位症

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摘要

Objective: The aim of this study was to investigate the efficacy of anti-interleukin 6 (IL-6) therapy in the treatment of endometriosis in a rat model.

机译：目的：本研究的目的是研究抗白介素6（IL-6）治疗大鼠子宫内膜异位症的疗效。

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来源
《Reproductive sciences》 |2016年第5期|共8页
作者
Taskin Mine Islimye; Gungor Aysenur Cakir; Adali Ertan; Yay Arzu; Onder Gozde Ozge; Inceboz Umit;
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正文语种 eng
中图分类产科学;
关键词
IL-6; tocilizumab; endometriosis; rat model;

机译：IL-6;托珠单抗;子宫内膜异位症;大鼠模型;

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1. A Humanized Anti-Interleukin 6 Receptor Monoclonal Antibody, Tocilizumab, for the Treatment of Endometriosis in a Rat Model [J] . Taskin Mine Islimye, Gungor Aysenur Cakir, Adali Ertan, Reproductive sciences . 2016,第5期

机译：人源化抗白介素6受体单克隆抗体Tocilizumab，用于治疗大鼠子宫内膜异位症
2. Tocilizumab: A novel humanized anti-interleukin 6 (IL-6) receptor antibody for the treatment of patients with non-RA systemic, inflammatory rheumatic diseases [J] . AltenR., MaleitzkeT. Annals of medicine . 2013,第3a4期

机译：Tocilizumab：一种新型人源化抗白介素6（IL-6）受体抗体，用于治疗非RA系统性炎性风湿病患者
3. Tocilizumab: A Novel Humanized Anti-Interleukin 6 Receptor Antibody for the Treatment of Patients with Rheumatoid Arthritis [J] . Rieke Alten Therapeutic advances in musculoskeletal disease. . 2011,第3期

机译：Tocilizumab：一种新型的人源化抗白介素6受体抗体，用于治疗类风湿关节炎患者
4. Humanization of an Anti-CD34 Monoclonal Antibody by Complementarity-Zetermining Region Grafting Based on Computer-assisted Molecular Modelling [C] . Sheng Hou, Bohua Li, Ling Wang, 第四届国际分子模拟与信息技术应用学术会议（The 4th International Conference of Molecular Simulations and Applied Informatics Technologies）论文集 . 2008

机译：基于计算机辅助分子建模的互补决定区接枝人源化抗CD34单克隆抗体
5. Cloning and expression of a biosimilar chimeric monoclonal antibody directed against the human epidermal growth factor receptor and its production in CHO cells for treatment of colo-rectal cancer. [D] . Motiwala, Hatim Maqbulhusen. 2012

机译：针对人表皮生长因子受体的生物仿制药嵌合单克隆抗体的克隆和表达及其在CHO细胞中的产生，用于治疗结肠直肠癌。
6. Tocilizumab: A Novel Humanized Anti-Interleukin 6 Receptor Antibody for the Treatment of Patients with Rheumatoid Arthritis [O] . Rieke Alten 2011

机译：Tocilizumab：一种新型的人源化抗白介素6受体抗体用于治疗类风湿关节炎患者
7. Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis [O] . 2009

机译：日本风湿病学会2009年关于类风湿关节炎使用人源化抗白介素6受体单克隆抗体tocilizumab的指南

A Humanized Anti-Interleukin 6 Receptor Monoclonal Antibody, Tocilizumab, for the Treatment of Endometriosis in a Rat Model

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