4,5-Dihydroxyimidazolidin-2-ones in the reaction of α-ureidoalkylation of N-(carboxyalkyl)-,N-(hydroxyalkyl)-, and N-(aminoalkyl)ureas 6.* Tandem sequence of α-ureidoalkylation and esterification in the course of the reaction of N- (carboxyalkyl)ureas with 4,5-dihydroxy-1,3-dimethyl-4,5-diphenylimidazolidin-2-one in alcohols

摘要

It was found for the first time that the reaction of N-(carboxyalkyl)ureas (ureido acids) with 4,5-dihydroxy-1,3-dimethyl-4,5-diphenylimidazolidin-2-one in methyl or isopropyl alcohol proceeds through the tandem sequence of α-ureidoalkylation and esterification to form the earlier unknown N-(carboxyalkyl)glycoluril methyl or isopropyl esters. N-(Carboxyalkyl)-glycolurils of a new-type substitution were obtained by alkaline hydrolysis of their isopropyl esters, the structure of one of them was confirmed by X-ray diffraction analysis.