A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis

Julia Antonio; Gonzalez Isidoro; Fernandez-Nebro Antonio; Blanco Francisco; Rodriguez Luis; Gonzalez Antonio; Canete Juan D.; Maymo Joan; Alperi-Lopez Mercedes; Olive Alejandro; Corominas Hector; Martinez-Taboada Victor; Erra Alba; Sanchez-Fernandez Simon; Alonso Arnald; Lopez-Lasanta Maria; Tortosa Raul; Codo Laia; Gelpi Josep Lluis; Garcia-Montero Andres C.; Bertranpetit Jaume; Absher Devin; Bridges S. Louis Jr.; Myers Richard M.; Tornero Jesus; Marsal Sara

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A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis

机译：全基因组关联研究确定SLC8A3是ACPA阳性类风湿关节炎的易感基因座

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Objective. RA patients with serum ACPA have a strong and specific genetic background. The objective of the study was to identify new susceptibility genes for ACPA-positive RA using a genome-wide association approach.

机译：目的。患有ACPA血清的RA患者具有很强的特异性遗传背景。该研究的目的是使用全基因组关联方法为ACPA阳性RA识别新的易感基因。

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来源
《Rheumatology》 |2016年第6期|共6页
作者
Julia Antonio; Gonzalez Isidoro; Fernandez-Nebro Antonio; Blanco Francisco; Rodriguez Luis; Gonzalez Antonio; Canete Juan D.; Maymo Joan; Alperi-Lopez Mercedes; Olive Alejandro; Corominas Hector; Martinez-Taboada Victor; Erra Alba; Sanchez-Fernandez Simon; Alonso Arnald; Lopez-Lasanta Maria; Tortosa Raul; Codo Laia; Gelpi Josep Lluis; Garcia-Montero Andres C.; Bertranpetit Jaume; Absher Devin; Bridges S. Louis Jr.; Myers Richard M.; Tornero Jesus; Marsal Sara;
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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
关键词
rheumatoid arthritis; anti-citrullinated protein antibodies; joint erosions; genetic risk; genome-wide association study;

机译：类风湿关节炎;抗瓜氨酸化蛋白抗体;关节侵蚀;遗传风险;全基因组关联研究;

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1. A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis [J] . Julia Antonio, Gonzalez Isidoro, Fernandez-Nebro Antonio, Rheumatology . 2016,第6期

机译：全基因组关联研究确定SLC8A3是ACPA阳性类风湿关节炎的易感基因座
2. Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome-Wide Association Study [J] . Orozco Gisela, Viatte Sebastien, Bowes John, Arthritis & rheumatology. . 2014,第1期

机译：在英国扩展的基因组-范围协会研究中确定了22q12的新型类风湿关节炎易感性基因座
3. Novel Rheumatoid Arthritis Susceptibility Locus at 22ql2 Identified in an Extended UK Genome-Wide Association Study [J] . Gisela Orozco, Sebastien Viatte, John Bowes, Arthritis and Rheumatism . 2014,第1期

机译：扩展的英国基因组-范围协会研究中确定的22ql2的新型类风湿关节炎易感基因座
4. Data analysis of Genome-Wide Association studies (GWAS) concerning rheumatoid arthritis and multiple sclerosis [C] . 10th IEEE International Conference on Information Technology and Applications in Biomedicine . 2010

机译：类风湿关节炎和多发性硬化症的全基因组关联研究（GWAS）的数据分析
5. Investigating the Role of Long Non-coding RNA Genetically Associated with Rheumatoid Arthritis Susceptibility [D] . Ding, James E. 2018

机译：调查长期非编码RNA遗传与类风湿性关节炎易感性相关的作用
6. Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome-Wide Association Study [O] . Gisela Orozco, Sebastien Viatte, John Bowes, -1

机译：在英国扩展的基因组-范围协会研究中确定了22q12的新型类风湿关节炎易感性基因座
7. A genome-wide association study identifiesSLC8A3as a susceptibility locus for ACPA-positive rheumatoid arthritis [O] . Antonio Julià, Isidoro González, Antonio Fernández-Nebro, 2016

机译：基因组关联研究标识为ACPA阳性类风湿性关节炎的易感位点

A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis

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