Multiple numerical chromosome aberrations in carcinogenesis: The kidney cancer model

摘要

This letter summarizes the talk I gave at the 2nd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects, in Oakland, California, after the kind invitation of Peter Duesberg from the University of California, Berkeley. The conference addressed the issue of whether aneuploidy or gene mutations are the driving force behind the development of cancer. I chose to focus on the kidney cancer model because it gives good arguments to both sides of the fence, having therefore the potential to stimulate a fruitful dis-cussion. So, why is the kidney cancer model so interesting?#