Rapidly exchanging Ca2+ stores: Ubiquitous partners of surface channels in neurons

摘要

Neuronal rapidly exchanging Ca2+ stores coincide with the endoplasmic reticulum and possess ample, nonrandom distribution, dual receptor channels, IP3 and ryanodine receptors, and heterogeneous membranes. Because of these properties, the stores are able to reinforce and expand the Ca2+ signals generated at the surface, working as partners of voltage- and receptor-gated channels.