Highly efficient and chemoselective method for the thioacetalization of aldehydes and transthioacetalization of aeetals and acylals catalyzed by H2SO4-silica under solvent-free conditions

摘要

Chemoselective and efficient thioacetalization of a variety of aldehydes was achieved in excellent yields at room temperature using 1,2-ethanedithiol in the presence of catalytic amounts of H2SO4-silica. Thioacetals were also prepared by transthioacetalization of acylals and acetals under similar conditions.