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首页> 外文期刊>Neurourology and urodynamics. >Do preoperative urodynamics still have a role in female stress urinary incontinence? Re: Van Leijsen SA, Kluivers KB, Mol BW, et al. Can Preoperative Urodynamic Investigation be Omitted in Women with Stress Urinary Incontinence? A Non-Inferiority Randomized Controlled Trial. Neurourol Urodyn 2012;31:1118-23
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Do preoperative urodynamics still have a role in female stress urinary incontinence? Re: Van Leijsen SA, Kluivers KB, Mol BW, et al. Can Preoperative Urodynamic Investigation be Omitted in Women with Stress Urinary Incontinence? A Non-Inferiority Randomized Controlled Trial. Neurourol Urodyn 2012;31:1118-23

机译:术前尿流动力学仍然在女性压力性尿失禁中起作用吗?回复:Van Leijsen SA,Kluivers KB,Mol BW等。压力性尿失禁妇女可以省略术前尿动力学检查吗?非劣效性随机对照试验。 Neurourol Urodyn 2012; 31:1118-23

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The interesting randomized controlled trial by van Leijsen et al. concerns one of the most relevant and actually debated issue in urogynecology, the role of urodynamics in the preop-erative evaluation of women with stress urinary incontinence (SUI). Some articles, also very recently published, seem to show that preoperative urodynamics do not improve the effectiveness of surgery in patients treated with midurethral slings placements for SUI. However, the last recommendations of the International Consultation on Incontinence suggest to perform urodynamic assessment before SUI surgery. The article by Van Leijsen et al. could be an important intellectual and clinical impact in the preoperative management of SUI. However, this trial presents some relevant limitations that could partially invalidate the obtained finding. The authors included in their study population also women with mixed urinary incontinence and they did not specify how they determined predominant stress incontinence. In spite of this potentially biasing enlargement of the patients recruitment and of the involvement of 10 different hospital, the authors enrolled in their trial only 59 women with SUI; this is a very small subset of patients, thus resulting in a very low statistical power for a minimal clinically relevant difference. Moreover, the study did not include or describe the women that more likely could benefit from urodynamics, patients with low leak point pressure, low MUCP, pelvic organ prolapse, previous failed incontinence or prolapse surgery or voiding dysfunction. Several papers identified new and classical urodynamic parameters to predict the sling outcomes (MUCPP, VLPP, open vesical pressure) and to offer to the patients a more accurate preoperative counselling.
机译:van Leijsen等人的有趣的随机对照试验。涉及泌尿妇科学中最相关,最受争议的问题之一,即泌尿动力学在压力性尿失禁妇女术前评估中的作用。一些文章(也即将在最近发表)似乎表明,术前尿流动力学不能改善接受SUI尿道中吊带治疗的患者的手术效果。但是,国际失禁咨询委员会的最后建议建议在SUI手术前进行尿动力学评估。 Van Leijsen等人的文章。可能对SUI的术前管理产生重要的智力和临床影响。但是,该试验存在一些相关局限性,可能会部分抵消所获得的发现。在研究人群中还包括混合性尿失禁的女性,他们没有说明如何确定主要的压力性尿失禁。尽管这可能会增加患者招募的偏见,并增加了10家不同医院的参与,但作者仅将59名SUI妇女纳入了他们的试验。这是一个很小的患者子集,因此导致临床相关差异最小的统计功效非常低。而且,该研究未包括或描述那些更可能从尿流动力学,低漏点压力,低MUCP,骨盆器官脱垂,先前的失禁或脱垂失败或脱垂功能障碍患者中受益的妇女。几篇论文确定了新的经典尿动力学参数,以预测吊索结局(MUCPP,VLPP,开放性膀胱压力)并为患者提供更准确的术前咨询。

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